Periarterite noueuse: complications digestives et cardio-vasculaires a propos d'un cas

Polyarteritis nodosa [PAN] is a necro-tizing systemic vasculitis involving the wall of small and medium sized arteries. The histologic aspect is defined by the presence of fibrinoid necrosis and an infiltrate rich in neutrophil polynuclears in the artery wall and rare granulomas. Clinical manifestations are misleading, and more often the symptoms of the disease are retrospectively related to the PAN. The gastrointestinal involvement carries a poor prognosis. We report a clinical case of severe PAN concerning a 46-year-old woman revealed by an acute alithi-asic cholecystitis, needing a cholecystectomy. A number of complications occurred during the evolution and we noticed the occurrence of cutaneous ulcers, a number of ischemic accidents like a necrosis of toes of right leg, a minimal myocardial infarction, a pneu-matosis of the small intestin. Three months later, under treatment by prednisone and cyclophosphamide, the patient developped an ischemic perforation of the Despite an urgent surgery a rapid and fatal evolution was observed. A discussion of the case and a review of the literature will be presented

propos d'un syndrome de gougerot-Sjogren associe a une sclerose en plaques

Gougerot-Sjogern Syndrom [GSS] is one of the more frequent auto-immune disease; yet, its etiology remains unknown. Neurological involvement is considered in around 20% of GSS cases, and in most cases, peripheral nervous system is concerned while central nervous lesions are still controversial with regard of their incidence and pathophysiology. In rare cases, multiple white matter demeylinating lesions involving brain and spinal cord have been reported as of inflammatory nature that mimic Multiple Sclerosis [MS] lesions. We report a case highly suggestive of GSS associated with a replasing remitting MS in a patient based on Poser's MS criteria

Cohorte de 23 patients Libanais porteurs d'un syndrome de Gougerot - Sjogren primitif

Gougerot-Sjogren Syndrome is a autoimmune disease in Lebanon. A retrospective study including 23 patients selected according to european criteria allowed to evaluate glandular and extra glandular mainfestations, to correlate histological, clinical and biological results, to place the histological of the minor salivary glands in the general diagnostic frame and to relate epidemiological characteristics linked to the family aspect of the syndrome